Prime Inc.
$50,000 - $80,000+OTR, Regional, Refrigerated, Tanker, Flatbed
Moderate Demand
Over-the-Road (OTR) Jobs in Missouri
Browse otr trucking positions across Missouri with top carriers hiring now.
Average Pay
$54,000 - $83,000
Demand Level
Moderate
Top Carriers
5+ Hiring
Key Cities
5+ Markets
OTR Trucking in Missouri
Missouri is positioned in the heart of America's freight network where major interstates intersect. OTR drivers based here can reach 80% of the U.S. population within a single driving shift, making it a prime location for long-haul carriers. Demand for OTR drivers in Missouri is moderate, with carriers actively recruiting experienced drivers and offering competitive sign-on bonuses. The state's strategic location keeps freight volumes consistent year-round.
Top Companies Hiring OTR Drivers in MO
View Company
Anderson Trucking Service
$65,000 - $95,000OTR, Regional, Flatbed, Specialized, Owner-Operator
Covenant Transport
$50,000 - $80,000OTR, Regional, Dedicated, Team, Expedited
Crete Carrier Corporation
$55,000 - $85,000OTR, Regional, Dedicated, Refrigerated, Flatbed
CRST International
$48,000 - $80,000OTR, Regional, Dedicated, Team, Flatbed
Driving jobs we are recruiting for in Missouri
Each of these is a live posting with the pay, home time and requirements set out in full. Applying takes about a minute.
OTR Dry Van Driver
$52,500 - $74,000/year · Out 2–3 weeks
OTR Reefer Driver
$57,000 - $80,500/year · Out 2–3 weeks
OTR Flatbed Driver
$58,500 - $82,500/year · Out 1–2 weeks
OTR Step Deck Driver
$59,500 - $84,000/year · Out 1–2 weeks
OTR Tanker Driver
$60,000 - $85,000/year · Out 1–2 weeks
OTR Hazmat Driver
$61,500 - $87,000/year · Out 1–2 weeks
OTR Car Hauler Driver
$62,500 - $88,500/year · Out 2–3 weeks
OTR Oversized Driver
$66,000 - $93,000/year · Out 2–3 weeks
Regional Intermodal Driver
$53,500 - $75,500/year · Home weekly
Local Box Truck Driver
$44,000 - $62,000/year · Home daily
Regional Dump Truck Driver
$49,500 - $70,000/year · Home most nights
Local Cement Mixer Driver
$50,000 - $71,000/year · Home daily
OTR Hotshot Driver
$54,500 - $77,000/year · Out 1–2 weeks
Regional Less Than Truckload Driver
$55,500 - $78,500/year · Home weekly
OTR Power Only Driver
$52,500 - $74,000/year · Out 2–3 weeks
Local Straight Truck Driver
$43,000 - $60,500/year · Home daily
Top Cities for OTR Jobs in Missouri
Kansas City
Missouri
St. Louis
Missouri
Springfield
Missouri
Columbia
Missouri
Joplin
Missouri
Key Freight Routes in Missouri
1
I-70 (Kansas City to St. Louis)
2
I-44 (Springfield to St. Louis)
3
I-35 (Kansas City north-south)
Requirements for OTR Driving in MO
- Valid CDL-A license
- Minimum 6 months verifiable OTR experience (some carriers accept new graduates)
- Clean MVR with no major violations in the past 3 years
- DOT physical card (medical examiner's certificate)
- Ability to pass pre-employment drug screening
- Must be at least 21 years old for interstate driving
Start Your OTR Driving Career in Missouri
Submit your application and get matched with companies hiring otr drivers in MO.
OTR Trucking Jobs in Missouri — FAQs
How much do otr truck drivers make in Missouri?
OTR truck drivers in Missouri earn $54,000 - $83,000 annually, depending on experience, endorsements, and carrier. Missouri's central location and freight density help drivers maintain consistent miles, which translates to strong annual earnings. Sign-on bonuses are widely advertised in this market, but the amount, the qualifying period and the clawback terms differ by carrier — read the offer letter rather than the recruiting ad, and ask when the money actually lands.
What are the best OTR trucking routes through Missouri?
Missouri's interstate system connects drivers to major freight lanes across the region. Outbound loads from Missouri typically move to distribution hubs in neighboring states, while inbound freight includes consumer goods, raw materials, and manufacturing inputs. Carriers based in or running through MO offer consistent miles with multiple routing options.
Are trucking companies in Missouri hiring otr drivers in 2026?
Yes — otr driver demand in Missouri is moderate heading into 2026. The otr segment in Missouri is expanding, with carriers adding routes and increasing hiring as freight volumes grow. Check individual carrier listings for current openings and application requirements in MO.